Which of the following is NOT a valid operation that can be performed on cells in a spreadsheet?

Creating a new spreadsheet without any software is indeed not a valid operation that can be performed on cells in a spreadsheet. Spreadsheets are typically created and manipulated using specialized software, such as Microsoft Excel, Google Sheets, or similar programs. The process of creating a new spreadsheet inherently requires software designed to handle spreadsheet functions.

On the other hand, the other options represent valid operations within the context of spreadsheet software. Editing text in a cell allows users to modify the contents directly. Changing the font style of a cell enables customization of how the text appears, which can enhance readability or highlight important information. Arranging cells based on their content involves sorting data, which is a fundamental feature for organizing information effectively. Each of these operations enhances the usability and functionality of a spreadsheet, but they all depend on the presence of proper software to perform them.